Early to mid-60s there was a 409 offered in medium (60 & 70 series) trucks. I have no idea if that differed from the car engine or not.
The Schwann's Ice Cream folsk are running a whole fleet of propane powered 366s that are probably in the 98-02/3 age range.
There's a guy a few miles from here running a 6 yd dump on a C60 chassis in the 68-72 body style. That has the louvers you're talking about with the 427 badge on it. The drivers side louver was functional, there's an air duct leading to the carb with a big foam seal to match up to the louvered opening.
I just dug out my 1970 GM truck shop manual and got he following specs.
350, 4 bbl, 255 hp, 355 ft lbs torque, available only in 10-20-30 series
350. 2 bbl, 215 ho, 335 ft lbs torque, available in the 40 and 50 series
366, 4 bbl, 235 hp, 345 ft lbs torque, available in the 60 series
427, 4bbl, 260 hp, 405 ft lbs torque, available in the 60 series
There was a 400 used in the 10-30 series, 310 hp and 400 torque, and three diesels, a 3-53N in PT30 (probably a bread van style) which made a whopping 82 hp and 193 lbs torque, a 4-53n in the CD50, making 130 hp and 278 torque and a V-6, DH478 with 165 and 337 for output.
My 1971 C5500 came with the 350, 2 bbl version which I swapped to an Edelbrock Performer intake and 600 Holley. That makes a very driveable powerplant for a truck grossing 20-22K. Transmission is an SM465 with a two speed rear having (if I remember right) 6.62 & 8.85 high and low ranges respectively.