I agree with everything Chris said in his above post. On a 24V,you do not need a free flowing air cleaner,and exhaust right away.You can add more power with just a minor fueling box.The air cleaner,exhaust does help,but it isnt necessay until about 325hp.The auto trans is a sore spot on these trucks.It needs to be addressed with some trucks as soon as you add more than 50hp,others will hold 75hp or so extra.
IMO for most people who arent happy with just a small box,they will need to do some trans work.Sometimes just a shft kit will hold things together for a while.To be honest though I recommend upgrading the entire trans at this time.If your going to pull the trans out,and go into it you might as well go thru the whole thing. Once the trannys done(this is by far the single biggest expense),you can add more power.I recommend diesel dynamics stage 2 injectors for 90% of the 24V trucks. This combined with a minor fueling box will deliver more power than you could ever need,and the torque will be unbeleivable.the truck wil be around 310-320RWHP at this point with about 700-750 ft lbs at the rear wheels,from 1500RPM on up..Driveablity will be excellent,very smooth and powerful.If you need more.get a major fueling box,and do some fuel system work (address the weak lift pump),then add a larger turbo and 400-450hp RWHP is about where you'll be,with about 850 ft lbs at the wheels.AT this point if your still not happy there are step 4 injectors and EDM injectors that will get you to about 500hp with a single turbo.If you want more than 500HP you need to go twin turbos or use Nitrous. Building these trucks is very fun,and satisfying,but it isnt cheap. i think reliability is great to about 475hp.At this point the boost you make starts to get to the point where you may blow the head gasket,also the EGTSs get high with a single turbo.The transfer case,rear ends,and axles have all been very reliable from my experience.
On the 12v trucks,simply putting in a torque plate,and governor spring kit will take the truck to the point of needing tranny work.If more is wanted turbo changes,and injector changes will be needed.
Anyone needing more info feel free to Pm me,I have made some mistakes building mine,and if i coud do it over id save a lot of time,and money.